Approximately half of Ghana’s overall population has access to electricity and, of this, much of it is in urban areas. Often in regions where modern energy is not available, kerosene lamps, for example, are used for indoor lighting. This produces harmful emissions, leading to poor respiratory effects. Implementation of hydrokinetic power (HKP) within nearby streams can provide low impact, robust energy to rural communities. Such a system lends itself to a simple design with ease of maintenance, which can be used as a stand-alone power system (SAPS). With Ghana’s renewable energy policies coming to fruition, it is sought to establish the economic viability and sustainability of this technology. This paper discusses site selection and the HKP technology in rural areas of Ghana.